The greatly feared Sinaloan Cartel was run by Joaquin “El Chapo” Guzman-Loera, Ismael “El Mayo” Zambada, and Hector “El Guero” Palma-Salazar who was arrested June 1995, in Guadalajara, Jalisco, Mexico, at the home of a police commander. Over 30 federal police officers were also arrested for providing him protection. Palma-Salazar was extradited, placed into federal custody, and put on trial in the U.S. for drug trafficking charges. He was confined at the U.S. Supermax-ADX prison in Florence, CO, with a maximum release date of July 16, 2016. Meanwhile, “El Chapo” was arrested in 1993, but escaped in 2001 from a Mexican prison in a laundry cart with inside help. This was just before he was about to be extradited to the U.S.
While the Cartel has been known to kill if need be, it has preferred to buy power brokers off, than "wack them" thus creating fewer enemies. As far as their drug dealing rivals; however, they will use whatever resources at their deposal. The Cartel also wisely does not get involved in the leadership of its business partners so what affects their "headquarters" does not necessarily affect "subsidiaries" and visa-versa because there is little top to bottom control.